Best Mouse for Work in 2025 – Top Picks for Productivity and Comfort

When you spend hours at your desk each day, the right mouse can make a world of difference. Whether you’re crunching numbers, designing graphics, or managing endless emails, a reliable and ergonomic mouse is more than just a tool—it’s an investment in your comfort and productivity.

Unlike gaming mice that prioritize speed and flashy aesthetics, a work mouse focuses on precision, ergonomics, long battery life, and multi-device connectivity. With the rise of hybrid and remote work setups, choosing the best mouse is no longer about just clicking and scrolling—it’s about efficiency, health, and adaptability.

In this guide, we’ve rounded up the best mice for work in 2025 that balance performance, comfort, and value. Let’s dive into the top options that professionals swear by.

🖱️ Top Picks for the Best Mouse for Work

1. Logitech MX Master 3S

Estimated Price: $95 – $110

Product Details:
The Logitech MX Master 3S is widely considered the gold standard for productivity. Designed for professionals, it offers ultra-precise tracking (8,000 DPI), ergonomic support for long hours, and seamless switching between up to three devices. The MagSpeed scroll wheel is nearly silent yet incredibly fast, making it perfect for spreadsheets and documents.

Pros:

• Exceptional ergonomics for all-day comfort
• Multi-device and cross-platform compatibility
• Quiet and precise MagSpeed scrolling
• Long battery life (70 days per charge)

Cons:

• On the pricier side
• May feel bulky for users with smaller hands

2. Microsoft Surface Precision Mouse

Estimated Price: $80 – $95

Product Details:
The Surface Precision Mouse is ideal for professionals in design, finance, and office work. It features a smooth scroll, three customizable buttons, and the ability to connect to three devices simultaneously. Its comfortable, sculpted design reduces strain during long working hours.

Pros:

• Great for multi-taskers with multi-device pairing
• Sleek, premium build quality
• Smooth, accurate tracking
• Excellent battery life

Cons:

• Limited customization compared to Logitech
• Slightly heavy for travel use

3. Anker Vertical Ergonomic Mouse

Estimated Price: $25 – $30

Product Details:
If ergonomics and affordability are your priority, the Anker Vertical Ergonomic Mouse is a fantastic choice. Its vertical design reduces wrist strain by keeping your hand in a more natural handshake position, making it popular among office workers with repetitive strain issues.

Pros:

• Affordable ergonomic solution
• Reduces wrist and forearm strain
• Lightweight and easy to use

Cons:

• Not ideal for small hands
• Takes time to get used to vertical grip
• Lacks advanced productivity features

4. Logitech MX Anywhere 3

Estimated Price: $75 – $85

Product Details:
For professionals who travel often, the Logitech MX Anywhere 3 is a compact yet powerful option. Despite its small size, it offers precise tracking on nearly any surface, including glass. The MagSpeed scroll and multi-device support make it a versatile tool for work on the go.

Pros:

• Compact and portable
• Tracks on almost any surface
• Multi-device support
• Long battery life

Cons:

• Smaller size not comfortable for long use
• Lacks side scroll wheel

5. Razer Pro Click

Estimated Price: $95 – $120

Product Details:
Designed in collaboration with Humanscale, the Razer Pro Click combines professional productivity with ergonomic comfort. Unlike Razer’s gaming-focused models, this mouse is built for office work, offering a right-handed ergonomic shape, long battery life (up to 400 hours via Bluetooth), and 8 programmable buttons for shortcuts. Its sleek white-and-gray design also makes it a stylish addition to any workstation.

Pros:

• Ergonomic design for reduced strain
• Up to 400 hours battery life on Bluetooth
• 8 programmable buttons for workflow efficiency
• Stylish, professional design

Cons:

• Premium price tag
• Best suited for right-handed users only
• No horizontal scroll like the Logitech MX series

Conclusion

Choosing the best mouse for work ultimately depends on your needs. If you want the ultimate productivity tool, the Logitech MX Master 3S is unbeatable. For a sleek and premium experience, the Microsoft Surface Precision Mouse is a strong contender. Those looking for budget-friendly ergonomics should consider the Anker Vertical Mouse, while frequent travelers will love the portability of the Logitech MX Anywhere 3.

A good work mouse isn’t just about convenience—it’s about preventing fatigue, boosting efficiency, and enhancing your workflow. Investing in the right one will pay off every single day you use it.

A good work mouse isn’t just about convenience—it’s about preventing fatigue, boosting efficiency, and enhancing your workflow. Pair it with some wireless gadgets to keep your desk clutter-free, and you’ll have a workspace that’s both productive and comfortable.